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Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/15109

Title: An outbreak of aflatoxin poisoning in dogs associated with aflatoxin B1-contaminated maize products
???metadata.dc.creator???: Wouters, Angelica Terezinha Barth
Casagrande, Renata Assis
Wouters, Flademir
Watanabe, Tatiane Terumi Negrão
Boabaid, Fabiana Marques
Driemeier, David
Keywords: Dogs – Diseases
Corn starch
Food contamination
Aflatoxins
Cão – Doenças
Amido de milho
Alimentos – Contaminação
Aflatoxinas
Publisher: American Association of Veterinary Laboratory Diagnosticians
Issue Date: Mar-2013
Citation: WOUTERS, A. T. B. et al. An outbreak of aflatoxin poisoning in dogs associated with aflatoxin B1-contaminated maize products. Journal of Veterinary Diagnostic Investigation, [Visalia], v. 25, n. 2, p. 282-287, Mar. 2013.
Abstract: An aflatoxicosis outbreak affected 65 dogs from 9 different farms after they were fed diets with cooked corn meal as a common ingredient. Of the dogs, 60 died. Numerous dogs died on additional farms, but those dogs were not included in the study. The farmers acquired the contaminated maize products, in the form of whole corn grain or as corn meal, from the same supplier. The corn product was mixed with meat that was left over from home or commercial rations to form corn polenta, which was fed to the dogs. Necropsy was performed on 3 dogs. Two of the dogs died after a few days of refusing food, showing anorexia, polydipsia, icteric mucous membranes, hematemesis, hematochezia, or melena, and bleeding of the skin, eye, ear, and mouth. The primary necropsy findings included jaundice, hemorrhages in several organs, and yellowish enlarged liver with enhanced lobular pattern. The dog that experienced chronic ascites had a yellowish liver with reduced volume, irregular surface, and increased consistency. The main histological findings included hepatocyte fatty degeneration, biliary duct hyperplasia, cholestasis and, in the chronic case, hepatic fibrosis. High-performance liquid chromatography analysis of the corn meal from 2 affected farms revealed 1,640 ppb and 1,770 ppb of aflatoxin B1, respectively. The current study demonstrates an additional way that dogs can be exposed to, poisoned, and killed by aflatoxin.
URI: http://journals.sagepub.com/doi/full/10.1177/1040638713477409
http://repositorio.ufla.br/jspui/handle/1/15109
???metadata.dc.language???: en_US
Appears in Collections:DMV - Artigos publicados em periódicos

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