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dc.creatorAndrade, Eric Francelino-
dc.creatorLima, Andressa Ribeiro Veiga-
dc.creatorNunes, Ingrid Edwiges-
dc.creatorOrlando, Débora Ribeiro-
dc.creatorGondim, Paula Novato-
dc.creatorZangeronimo, Márcio Gilberto-
dc.creatorAlves, Fernando Henrique Ferrari-
dc.creatorPereira, Luciano José-
dc.identifier.citationANDRADE, E. F. et al. Exercise and beta-glucan consumption (Saccharomyces cerevisiae) improve the metabolic profile and reduce the atherogenic index in type 2 diabetic rats (HFD/STZ). Nutrients, [S. l.], v. 8, n. 12, p. 1-11, 2016.pt_BR
dc.description.abstractPhysical activity and the ingestion of dietary fiber are non-drug alternatives commonly used as adjuvants to glycemic control in diabetic individuals. Among these fibers, we can highlight beta-glucans. However, few studies have compared isolated and synergic effects of physical exercise and beta-glucan ingestion, especially in type 2 diabetic rats. Therefore, we evaluated the effects beta-glucan (Saccharomyces cerevisiae) consumption, associated or not to exercise, on metabolic parameters of diabetic Wistar rats. The diabetes mellitus (DM) was induced by high-fat diet (HFD) associated with a low dose of streptozotocin (STZ—35 mg/kg). Trained groups were submitted to eight weeks of exercise in aquatic environment. In the last 28 days of experiment, animals received 30 mg/kg/day of beta-glucan by gavage. Isolated use of beta-glucan decreased glucose levels in fasting, Glycated hemoglobin (HbA1c), triglycerides (TAG), total cholesterol (TC), low-density lipoprotein (LDL-C), the atherogenic index of plasma. Exercise alone also decreased blood glucose levels, HbA1c, and renal lesions. An additive effect for reducing the atherogenic index of plasma and renal lesions was observed when both treatments were combined. It was concluded that both beta-glucan and exercise improved metabolic parameters in type 2 (HFD/STZ) diabetic rats. View Full-Textpt_BR
dc.subjectDietary fiberspt_BR
dc.subjectGlycemic controlpt_BR
dc.subjectMetabolic profilept_BR
dc.subjectDiabetes - Glycemic controlpt_BR
dc.subjectFibras dietéticaspt_BR
dc.subjectControle glicêmicopt_BR
dc.subjectPerfil metabólicopt_BR
dc.subjectDiabetes - controle glicêmicopt_BR
dc.titleExercise and beta-glucan consumption (Saccharomyces cerevisiae) improve the metabolic profile and reduce the atherogenic index in type 2 diabetic rats (HFD/STZ)he Atherogenic Index in Type 2 Diabetic Rats (HFD/STZ)pt_BR
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