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Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/342

Title: DNA-psoralen: single-molecule experiments and first principles Calculations
???metadata.dc.creator???: Rocha, M. S.
Lúcio, A. D.
Alexandre, S. S.
Nunes, R. W.
Mesquita, O. N.
Keywords: Estrutura de biomoléculas
Interações moleculares
DNA
Issue Date: 2011
Citation: ROCHA, M. S. et al. DNA-psoralen: single-molecule experiments and first principles calculations. Applied Physics Letters, New York, v. 95, n. 25, 2009.
Abstract: The authors measure the persistence and contour lengths of DNA-psoralen complexes, as a function of psoralen concentration, for intercalated and crosslinked complexes. In both cases, the persistence length monotonically increases until a certain critical concentration is reached, above which it abruptly decreases and remains approximately constant. The contour length of the complexes exhibits no such discontinuous behavior. By fitting the relative increase of the contour length to the neighbor exclusion model, we obtain the exclusion number and the intrinsic intercalating constant of the interaction. Ab initio calculations are employed in order to provide an atomistic picture of these experimental findings.
URI: http://repositorio.ufla.br/jspui/handle/1/342
???metadata.dc.language???: pt_BR
Appears in Collections:DEX - Artigos publicados em periódicos

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