Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/37626
metadata.artigo.dc.title: Fish oil reduces the proliferation of cells cultured from human breast and colorectal tumours: an in vitro study
metadata.artigo.dc.creator: Bonatto, Sandro J. R.
Yamaguchi, Adriana Aya
Coelho, Isabela
Nunes, Everson Araújo
Iagher, Fabíola
Fukushima, Jorge Itsuo
Saboia, Luciano V.
Fernandes, Luiz Claudio
metadata.artigo.dc.subject: Cancer
Fish oil
Human
Lipid hydroperoxides
metadata.artigo.dc.publisher: Elsevier
metadata.artigo.dc.date.issued: Dec-2015
metadata.artigo.dc.identifier.citation: BONATTO, S. J. R. et al. Fish oil reduces the proliferation of cells cultured from human breast and colorectal tumours: an in vitro study. Journal of Functional Foods, [S.l.], v. 19, part B, p. 941-948, Dec. 2015.
metadata.artigo.dc.description.abstract: Diet plays a key role in the aetiology of cancer. Some studies have shown that diets rich in n-3 polyunsaturated fatty acids (n-3 PUFA) reduce tumour growth. This study aimed to investigate the effects of fish oil, rich in n-3 PUFA, in cell proliferation and death of cells from breast and colorectal tumours. In the presence of 1:5 (v/v) dilution of fish oil, 1.8-fold reduction in cell proliferation (p < 0.05) was observed. In addition, the presence of fish oil at a 1:5 proportion led to 1.6-fold increase in the rate of apoptosis, 6.7-fold increase in hydroperoxides, and 5-fold reduction in necrosis (p < 0.0001).
metadata.artigo.dc.identifier.uri: https://www.sciencedirect.com/science/article/pii/S1756464615004429#!
http://repositorio.ufla.br/jspui/handle/1/37626
metadata.artigo.dc.language: en_US
Appears in Collections:DNU - Artigos publicados em periódicos

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