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|metadata.artigo.dc.title:||Seasonal variation on the contents of coumarin and Kaurane‐Type diterpenes in Mikania laevigata and M. glomerata leaves under different shade levels|
|metadata.artigo.dc.creator:||Bertolucci, Suzan Kelly V.|
Pereira, Ana Bárbara D.
Pinto, José Eduardo B. P.
Oliveira, Alaíde B.
Braga, Fernão C.
Cinnamic acid derivatives
Derivados do ácido cinâmico
|metadata.artigo.dc.publisher:||Verlag Helvetica Chimica Acta AG|
|metadata.artigo.dc.identifier.citation:||BERTOLUCCI, S. K. V.; PEREIRA, A. B. D.; PINTO, J. E. B. P.; OLIVEIRA, A. B.; BRAGA, F. C. Seasonal variation on the contents of coumarin and Kaurane‐Type diterpenes in Mikania laevigata and M. glomerata leaves under different shade levels. Chemistry & Biodiversity, [S. l.], v. 10, n. 2, p. 288-295, Feb. 2013.|
|metadata.artigo.dc.description.abstract:||Coumarin (1) and kaurane‐type diterpenes are considered the bioactive constituents of Mikania glomerata and M. laevigata, used in Brazil to treat respiratory affective disorders. The seasonal variation of 1, ortho‐coumaric acid (2), benzoylgrandifloric acid (3), cinnamoylgrandifloric acid (4), and kaurenoic acid (5) in leaves of both species, cultivated in full sunlight and under shade levels of 40 and 80%, was quantified by HPLC. Compound 2 was detected solely in M. laevigata in concentrations below the limit of quantification. Coumarin was not found in M. glomerata, whereas its concentration reached 0.94±0.24% (w/w) in M. laevigata farmed in summer under 80% shading. Both Mikania species produced higher amounts of kaurane diterpenes when cultivated in plenty of sunlight. Hence, maximum contents of 1 are reached in M. laevigata cultivated under high shading, but with reduced concentrations of 3–5. Conversely, M. glomerata should be cultivated under full sunlight and harvested in winter for highest concentrations of kaurane‐type diterpenes.|
|Appears in Collections:||DAG - Artigos publicados em periódicos|
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