Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?

Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/41526

Título :	Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?
Autor:	Abeygunasekera, Anuruddha Jayasinghe, Saroj
Palavras-chave:	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Corona COVID-19 Diethylcarbamazine (DEC)
Publicador:	Elsevier
Data da publicação:	Out-2020
Referência:	ABEYGUNASEKERA, A.; JAYASINGHE, S. Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19? Medical Hypotheses, [S.l.], v. 143, Oct. 2020.
Abstract:	SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19. Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority. The paper proposes evidence for the potential use of diethylcarbamazine (DEC) in the treatment of COVID-19. DEC has inhibitory effects on arachidonic acid metabolism to prostaglandins, little known anti-viral effects on animal retroviruses and demonstrated anti-inflammatory actions in animal models of lung inflammation indicating the need to explore this hypothesis further. We believe this is the first time DEC is being proposed to treat COVID-19.
URI:	https://www.sciencedirect.com/science/article/pii/S0306987720305636 http://repositorio.ufla.br/jspui/handle/1/41526
Idioma:	en_US
Aparece nas coleções:	FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19)

Arquivos associados a este item:

Não existem arquivos associados a este item.