Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/41766
Título : Could autism spectrum disorders be a risk factor for COVID-19?
Autor: Lima, Matheus Eugênio de Sousa
Barros, Levi Coelho Maia
Aragão, Gislei Frota
Palavras-chave: Coronavirus
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
COVID-19
Autism spectrum disorder
Publicador: Elsevier
Data da publicação: Nov-2020
Referência: LIMA, M. E. DE S.; BARROS, L. C. M.; ARAGÃO, G. F. Could autism spectrum disorders be a risk factor for COVID-19? Medical Hypotheses, [S.l.], v. 144, Nov. 2020.
Abstract: The coronavirus SARS-CoV-2 pandemia is infecting millions of people and some studies relate conditions that might increase the risk of developing a fatal course for the disease, such as diabetes, cardiovascular diseases and obesity. In COVID-19 physiopathology, one of the main inflammation mechanisms is the “cytokine storm”, causing a pro-inflammatory state, related to cardiac and pulmonary damage. There is also a less effective role of lymphocyte B and T in the humoral immunity due to the reduction of their proliferative response. The physiopathology of ASD (Autism Spectrum Disorder) involves several modifications at the genetic and at the immune level, such as the increase of inflammatory cytokines and abnormal immune response in several levels. We hypothesize that ASD could be a risk-factor as the other conditions are.
URI: https://www.sciencedirect.com/science/article/pii/S0306987720310719
http://repositorio.ufla.br/jspui/handle/1/41766
Idioma: en
Aparece nas coleções:FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19)

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