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metadata.artigo.dc.title: Monitoring of the action of drugs in melanoma cells by dynamic laser speckle
metadata.artigo.dc.creator: González-Peña, Rolando J.
Braga Junior, Roberto A.
Cibrián, Rosa M.
Salvador-Palmer, Rosario
Gil-Benso, Rosario
San Miguel, Teresa
metadata.artigo.dc.subject: Specke patterns
Dynamic laser speckle
Cellular activity
Padrões de specke
Mancha de laser dinâmica
Atividade celular
metadata.artigo.dc.publisher: SPIE May-2014
metadata.artigo.dc.identifier.citation: GONZÁLEZ-PEÑA, R. J. et al. Monitoring of the action of drugs in melanoma cells by dynamic laser speckle. Journal of Biomedical Optics, [S. l.], v. 19, n. 5, May 2014. DOI:
metadata.artigo.dc.description.abstract: This work presents the development of a protocol based on the dynamic laser speckle designed to monitor the reaction of cancer cells of line MEL-RC08 to the application of the drug Colcemid in two different concentrations: 0.2 and 0.4  μg/mL . The protocol was designed using the forward scattering approach with an He-Ne laser of 632.8 nm illuminating the samples, a control, and two variations of Colcemid, being monitored along 8 h. The data were analyzed numerically in the time and in the frequency domain, and the results presented the ability of the technique to monitor the action of the drug, particularly Colcemid (0.4  μg/mL ).
metadata.artigo.dc.language: en_US
Appears in Collections:DEG - Artigos publicados em periódicos

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