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http://repositorio.ufla.br/jspui/handle/1/4781| Title: | Rational design of small modified peptides as ACE inhibitors |
| Issue Date: | 29-Aug-2012 |
| Publisher: | European Federation for Medicinal Chemistry |
| Citation: | SILVA, D. G. et al. Rational design of small modified peptides as ACE inhibitors. Medicinal Chemistry Communications - MedChemComm, [S. l.], v. 3, p. 1290-1293, Aug. 2012. |
| Abstract: | Computer-assisted techniques and the strategy of combining chemical substructures were used to derive small modified peptides as potent angiotensin-converting enzyme (ACE) inhibitors. In addition to high potency, some of the predicted compounds are also shown to exhibit satisfactory pharmacokinetic parameters. |
| URI: | http://pubs.rsc.org/en/content/articlepdf/2012/md/c2md20214j http://repositorio.ufla.br/jspui/handle/1/4781 |
| Appears in Collections: | DCA - Artigos publicados em periódicos |
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