Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/57450
Título: In vitro antimicrobial susceptibility and genetic resistance determinants of streptococcus agalactiae isolated from mastitic cows in brazilian dairy herds
Palavras-chave: Antimicrobial resistance genes
Bovine diseases
Bovine mastitis
Doenças de bovinos
Mastite bovina
Data do documento: 2017
Editor: Universidade Estadual de Londrina
Citação: SILVA, J. R. da et al. In vitro antimicrobial susceptibility and genetic resistance determinants of streptococcus agalactiae isolated from mastitic cows in brazilian dairy herds. Semina: Ciências Agrárias, Londrina, v. 38, n. 4, 2017. Suplemento.
Resumo: Streptococcus agalactiae is one of the main causative agents of bovine mastitis and is associated with several economic losses for producers. Few studies have evaluated antimicrobial susceptibility and the prevalence of genetic resistance determinants among isolates of this bacterium from Brazilian dairy cattle. This work aimed to evaluate the frequency of the antimicrobial resistance genes ermA, ermB, mefA, tetO, tetM, aphA3, and aad-6, and in vitro susceptibility to the antimicrobials amikacin, erythromycin, clindamycin, tetracycline, gentamicin, penicillin, ceftiofur, and cefalotin, and the associations between resistance genotypes and phenotypes among 118 S. agalactiae isolates obtained from mastitic cows in Brazilian dairy herds. Of the resistance genes examined, ermB was found in 19 isolates (16.1%), tetO in 23 (19.5%), and tetM in 24 (20.3%). The genes ermA, mefA, aphA3, and aad-6 were not identified. There was an association between the presence of genes ermB, tetM, and tetO and phenotypic resistance to erythromycin, clindamycin, and tetracycline. Rates of resistance to the tested antibiotics varied, as follows: erythromycin (19.5%), tetracycline (35.6%), gentamicin (9.3%), clindamycin (20.3%), penicillin (3.4%), and amikacin (38.1%); conversely, all isolates were susceptible to ceftiofur and cefalotin. Antimicrobial resistance testing facilitates the treatment decision process, allowing the most judicious choice of antibiotics. Moreover, it enables regional and temporal monitoring of the resistance dynamics of this pathogen of high importance to human and animal health.
URI: http://repositorio.ufla.br/jspui/handle/1/57450
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