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Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/9791

Title: Anti-obesity effects of the administration of tournefortia paniculata cham extract on wistar rats subjected to a hypercaloric diet
???metadata.dc.creator???: Simão, Anderson Assaid
Ramos, Vinicius de Oliveira
Corrêa, Angelita Duarte
Sousa, Raimundo Vicente de
Marcussi, Silvana
Keywords: Obesity
Medicinal plants
Pharmacology
Antioxidants
Genotoxicity
Publisher: Instituto de Tecnologia do Parana, Nucleo de Informacao e Extensao Tecnologica
Issue Date: Jul-2015
Citation: SIMAO, A. A. et al. Anti-obesity effects of the administration of tournefortia paniculata cham extract on wistar rats subjected to a hypercaloric diet. Brazilian Archives of Biology and Technology, Curitiba, v.58, n.4, p. 494-503, 2015.
Abstract: The aim of this study was to evaluate the therapeutic and toxicologic effects of the administration of the powered vegetable extract and aqueous extract of Tournefortia paniculata leaves on Wistar rats, subjected to a hypercaloric diet for 42 days. The rats were divided into five groups and were given the following treatments by gavage: T0 (control) - 1.0 mL water day-1; T1 - aqueous extract containing 14 mg phenolic compounds kg-1 rat day-1; T2 - 14 mg quercetin kg-1 rat day-1; T3 - 50 mg powered vegetable extract from T. paniculata leaves (PVE) kg-1 rat day-1 and T4 - 100 mg PVE kg-1 rat day-1. The treatments did not significantly alter the weight, but were effective in reducing liver fat, glucose and serum triglycerides. The treatment T1 reduced food consumption and lipid peroxidation. None of the treatments showed genotoxic potential. Results showed that T. paniculata leaves possessed an anti-obesity potential. However, a more detailed study of the medicinal potential and characterization of phytochemicals in this plant would be still necessary for a better understanding of its mechanisms of action, enabling future applications in the treatment of this pathology or for various therapeutic purposes.
URI: http://repositorio.ufla.br/jspui/handle/1/9791
???metadata.dc.language???: en_US
Appears in Collections:DQI - Artigos publicados em periódicos

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