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dc.creatorSampaio, Olívia Moreira-
dc.creatorVieira, Lucas Campos Curcino-
dc.creatorBellete, Barbara Sayuri-
dc.creatorKing-Diaz, Beatriz-
dc.creatorLotina-Hennsen, Blas-
dc.creatorSilva, Maria Fátima das Graças Fernandes da-
dc.creatorVeiga, Thiago André Moura-
dc.identifier.citationSAMPAIO, O. M. et al. Evaluation of alkaloids isolated from Ruta graveolens as photosynthesis inhibitors. Molecules, Basel, v. 23, n. 10, p. 1-12, 2018. doi: 10.3390/molecules23102693.pt_BR
dc.description.abstractEight alkaloids (1–8) were isolated from Ruta graveolens, and their herbicide activities were evaluated through in vitro, semivivo, and in vivo assays. The most relevant results were observed for Compounds 5 and 6–8 at 150 μM, which decreased dry biomass by 20% and 23%, respectively. These are significant results since they presented similar values with the positive control, commercial herbicide 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU). Based on the performed assays, Compound 5 (graveoline) is classified as an electron-transport inhibitor during the light phase of photosynthesis, as well as a plant-growth regulator. On the other hand, Compounds 6–8 inhibited electron and energy transfers, and are also plant-growth inhibitors. These phytotoxic behaviors based on acridone and quinolone alkaloids may serve as a valuable tool in the further development of a new class of herbicides since natural products represent an interesting alternative to replace commercial herbicides, potentially due their low toxicity.pt_BR
dc.subjectRuta graveolenspt_BR
dc.subjectPhotosystem IIpt_BR
dc.subjectHill reaction inhibitorspt_BR
dc.subjectAcridone alkaloidspt_BR
dc.subjectInibidores da reação Hillpt_BR
dc.subjectAlcalóides de acridonapt_BR
dc.titleEvaluation of alkaloids isolated from Ruta graveolens as photosynthesis inhibitorspt_BR
Appears in Collections:DQI - Artigos publicados em periódicos

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