Fish oil reduces the proliferation of cells cultured from human breast and colorectal tumours: an in vitro study

Bonatto, Sandro J. R.; Yamaguchi, Adriana Aya; Coelho, Isabela; Nunes, Everson Araújo; Iagher, Fabíola; Fukushima, Jorge Itsuo; Saboia, Luciano V.; Fernandes, Luiz Claudio

Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/37626

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Campo DC	Valor	Idioma
dc.creator	Bonatto, Sandro J. R.	-
dc.creator	Yamaguchi, Adriana Aya	-
dc.creator	Coelho, Isabela	-
dc.creator	Nunes, Everson Araújo	-
dc.creator	Iagher, Fabíola	-
dc.creator	Fukushima, Jorge Itsuo	-
dc.creator	Saboia, Luciano V.	-
dc.creator	Fernandes, Luiz Claudio	-
dc.date.accessioned	2019-11-14T12:46:12Z	-
dc.date.available	2019-11-14T12:46:12Z	-
dc.date.issued	2015-12	-
dc.identifier.citation	BONATTO, S. J. R. et al. Fish oil reduces the proliferation of cells cultured from human breast and colorectal tumours: an in vitro study. Journal of Functional Foods, [S.l.], v. 19, part B, p. 941-948, Dec. 2015.	pt_BR
dc.identifier.uri	https://www.sciencedirect.com/science/article/pii/S1756464615004429#!	pt_BR
dc.identifier.uri	http://repositorio.ufla.br/jspui/handle/1/37626	-
dc.description.abstract	Diet plays a key role in the aetiology of cancer. Some studies have shown that diets rich in n-3 polyunsaturated fatty acids (n-3 PUFA) reduce tumour growth. This study aimed to investigate the effects of fish oil, rich in n-3 PUFA, in cell proliferation and death of cells from breast and colorectal tumours. In the presence of 1:5 (v/v) dilution of fish oil, 1.8-fold reduction in cell proliferation (p < 0.05) was observed. In addition, the presence of fish oil at a 1:5 proportion led to 1.6-fold increase in the rate of apoptosis, 6.7-fold increase in hydroperoxides, and 5-fold reduction in necrosis (p < 0.0001).	pt_BR
dc.language	en_US	pt_BR
dc.publisher	Elsevier	pt_BR
dc.rights	restrictAccess	pt_BR
dc.source	Journal of Functional Foods	pt_BR
dc.subject	Cancer	pt_BR
dc.subject	Fish oil	pt_BR
dc.subject	Human	pt_BR
dc.subject	Lipid hydroperoxides	pt_BR
dc.title	Fish oil reduces the proliferation of cells cultured from human breast and colorectal tumours: an in vitro study	pt_BR
dc.type	Artigo	pt_BR
Aparece nas coleções:	DNU - Artigos publicados em periódicos

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