Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/41765
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dc.creatorRoshanravan, Neda-
dc.creatorGhaffari, Samad-
dc.creatorHedayati, Mehdi-
dc.date.accessioned2020-07-08T19:32:47Z-
dc.date.available2020-07-08T19:32:47Z-
dc.date.issued2020-
dc.identifier.citationROSHANRAVAN, N.; GHAFFARI, S.; HEDAYATI, M. Angiotensin converting enzyme-2 as therapeutic target in COVID-19. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, [S.l.], v. 14, n. 4, p. 637-639, July/Aug. 2020.pt_BR
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1871402120301417pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/41765-
dc.description.abstractThe pandemic of coronavirus disease 2019 (COVID-19) is a global health emergency that poses a significant threat to world people’s health. This outbreak causes major challenges to healthcare systems. Given the lack of effective treatments or vaccine for it, the identification of novel and safe drugs against COVID-19 infection is an urgent need. Angiotensin-converting enzyme 2 (ACE2) is not only an entry receptor of the SARS-CoV-2 virus, the virus that causes COVID-19, but also can protect from lung injury. In this view, we highlighted potential approaches to address ACE2-mediated SARS-CoV-2 virus, including 1) delivering an excessive soluble form of ACE2 (recombinant human ACE2: rhACE2) and 2) inhibition of the interaction between SARS-CoV-2 virus and ACE2 by some compounds with competitive effects (morphine and codeine). Further clinical trials in this regard can reveal a more definite conclusion against the COVID-19 disaster.pt_BR
dc.languageen_USpt_BR
dc.publisherElsevierpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceDiabetes & Metabolic Syndrome: Clinical Research & Reviewspt_BR
dc.subjectCOVID-19pt_BR
dc.subjectSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)pt_BR
dc.subjectAngiotensin-converting enzyme 2 (ACE2)pt_BR
dc.subjectRecombinant human ACE2 (rhACE2pt_BR
dc.subjectMorphinept_BR
dc.subjectCodeinept_BR
dc.titleAngiotensin converting enzyme-2 as therapeutic target in COVID-19pt_BR
dc.typeArtigopt_BR
Aparece nas coleções:FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19)

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