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dc.creatorGonzález-Peña, Rolando J.-
dc.creatorBraga Junior, Roberto A.-
dc.creatorCibrián, Rosa M.-
dc.creatorSalvador-Palmer, Rosario-
dc.creatorGil-Benso, Rosario-
dc.creatorSan Miguel, Teresa-
dc.date.accessioned2020-12-16T17:59:38Z-
dc.date.available2020-12-16T17:59:38Z-
dc.date.issued2014-05-
dc.identifier.citationGONZÁLEZ-PEÑA, R. J. et al. Monitoring of the action of drugs in melanoma cells by dynamic laser speckle. Journal of Biomedical Optics, [S. l.], v. 19, n. 5, May 2014. DOI: https://doi.org/10.1117/1.JBO.19.5.057008.pt_BR
dc.identifier.urihttps://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-19/issue-05/057008/Monitoring-of-the-action-of-drugs-in-melanoma-cells-by/10.1117/1.JBO.19.5.057008.full?SSO=1pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/45915-
dc.description.abstractThis work presents the development of a protocol based on the dynamic laser speckle designed to monitor the reaction of cancer cells of line MEL-RC08 to the application of the drug Colcemid in two different concentrations: 0.2 and 0.4  μg/mL . The protocol was designed using the forward scattering approach with an He-Ne laser of 632.8 nm illuminating the samples, a control, and two variations of Colcemid, being monitored along 8 h. The data were analyzed numerically in the time and in the frequency domain, and the results presented the ability of the technique to monitor the action of the drug, particularly Colcemid (0.4  μg/mL ).pt_BR
dc.languageen_USpt_BR
dc.publisherSPIEpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceJournal of Biomedical Opticspt_BR
dc.subjectSpecke patternspt_BR
dc.subjectDynamic laser specklept_BR
dc.subjectCellular activitypt_BR
dc.subjectColcemidpt_BR
dc.subjectPadrões de speckept_BR
dc.subjectMancha de laser dinâmicapt_BR
dc.subjectAtividade celularpt_BR
dc.titleMonitoring of the action of drugs in melanoma cells by dynamic laser specklept_BR
dc.typeArtigopt_BR
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