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dc.creatorCanaan, Marcelo M.-
dc.creatorCanaan, Juliana C. Reis-
dc.creatorZangerônimo, Márcio G.-
dc.creatorAndrade, Eric F.-
dc.creatorGonçalves, Thais M. S. V.-
dc.creatorPereira, Michel C. A.-
dc.creatorLima, Renato R.-
dc.creatorPardi, Vanessa-
dc.creatorMurata, Ramiro M.-
dc.creatorPereira, Luciano J.-
dc.date.accessioned2022-06-14T20:21:09Z-
dc.date.accessioned2023-06-27T18:38:28Z-
dc.date.available2022-06-14T20:21:09Z-
dc.date.available2023-06-27T18:38:28Z-
dc.date.issued2021-11-
dc.identifier.citationCANAAN, M. M. et al. Yeast beta-glucans ingestion does not influence body weight: a systematic review and meta-analysis of pre-clinical studies. Nutrients, Basel, v. 13, n. 12, 4250, 2021. DOI: 10.3390/nu13124250.pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/57364-
dc.description.abstractDietary fiber supplementation has been studied as a promising strategy in the treatment of obesity and its comorbidities. A systematic review and meta-analysis were performed to verify whether the consumption of yeast beta-glucan (BG) favors weight loss in obese and non-obese rodents. The PICO strategy was employed, investigating rodents (Population), subjected to the oral administration of yeast BG (Intervention) compared to animals receiving placebo (Comparison), evaluating body weight changes (Outcome), and based on preclinical studies (Study design). Two reviewers searched six databases and the grey literature. We followed the PRISMA 2020 guidelines, and the protocol was registered on PROSPERO (CRD42021267788). The search returned 2467 articles. Thirty articles were selected for full-text evaluation, and seven studies remained based on the eligibility criteria. The effects of BG intake on body weight were analyzed based on obese (n = 4 studies) and non-obese animals (n = 4 studies). Even though most studies on obese rodents (75%) indicated a reduction in body weight (qualitative analysis), the meta-analysis showed this was not significant (mean difference −1.35 g—95% CI −5.14:2.45). No effects were also observed for non-obese animals. We concluded that the ingestion of yeast BG barely affects the body weight of obese and non-obese animals.pt_BR
dc.languageenpt_BR
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)pt_BR
dc.rightsacesso abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.sourceNutrientspt_BR
dc.subjectFungipt_BR
dc.subjectYeastpt_BR
dc.subjectBeta-glucanspt_BR
dc.subjectBody weighpt_BR
dc.subjectRodentspt_BR
dc.subjectObesitypt_BR
dc.subjectFungospt_BR
dc.subjectLeveduraspt_BR
dc.subjectBeta-glucanospt_BR
dc.subjectPeso corporalpt_BR
dc.subjectObesidadept_BR
dc.titleYeast beta-glucans ingestion does not influence body weight: a systematic review and meta-analysis of pre-clinical studiespt_BR
dc.typeArtigopt_BR
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