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|metadata.artigo.dc.title:||Effect of Psidium guajava (cv. Pedro Sato) fruit and extract on the lipidemia in hypercholesterolemic rats|
|metadata.artigo.dc.creator:||Freire, Juliana Mesquita|
Abreu, Celeste Maria Patto de
Duarte, Stella Maris da Silveira
Paula, Fernanda Borges Araújo de
Lima, Adriene Ribeiro
Simão, Anderson Assaid
Guava - Bioactive compounds
Goiaba - Compostos bioativos
|metadata.artigo.dc.identifier.citation:||FREIRE, J. M. et al. Effect of Psidium guajava (cv. Pedro Sato) fruit and extract on the lipidemia in hypercholesterolemic rats. Journal of Medicinal Plants Research, [S. l.], v. 7, n. 24, p. 1768-1773, June 2013.|
|metadata.artigo.dc.description.abstract:||The objective was to analyze the bioactive compounds of the fruit and the ethanolic/acetonicextract of the Pedro Sato guava and to study their effect on the liver mass versus body mass ratio, hepatic lipids, C-reactive protein and levels of total and fractionated cholesterol in hypercholesterolemic Wistar rats. 6 groups were used: non-hypercholesterolemic control, hypercholesterolemic control, non-hypercholesterolemic treated with fruit, hypercholesterolemic treated with fruit, non-hypercholesterolemic treated with extract, hypercholesterolemic treated with extract. The treatments received the samples at a dosage of 50 mg kg-1 daily for 42 days. This study showed that the daily consumption of a guava (100 g) can contribute 10.08% of the fiber and 68.47% of the vitamin C recommended, besides supplying considerable amounts of phenolic compounds. All the hypercholesterolemic animals treated with the samples presented a reduction in the total and fractionated cholesterol levels; however there was no difference for the liver mass versus body mass ratio, hepatic lipids and C-reactive protein. These results show the importance of the guava consumption in the control of the hypercholesterolemia in rats and it may prevent and reduce the risk of heart diseases.|
|Appears in Collections:||DQI - Artigos publicados em periódicos|
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