Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/40770
Title: A new complex of Palladium(II) with 2-furoic hydrazide: synthesis, characterization, theoretical calculations and biological studies
Keywords: Palladium complexes
Hydrazides
Hydrazones
DFT
Density functional theory
Antibacterial activity
Issue Date: 2013
Publisher: Croatian Chemical Society
Citation: SOUZA, G. D. de et al. A new complex of Palladium(II) with 2-furoic hydrazide: synthesis, characterization, theoretical calculations and biological studies. Croatica Chemica Acta, [S.l.], v. 86, n. 2, p. 201-206, 2013. DOI: 10.5562/cca2151.
Abstract: A new complex of palladium was isolated with 2-furoic hydrazide (FH) and characterized by spectroscopic methods. The results show that the ligand is coordinated to palladium by the basic nitrogen of NH2 group and has a general structure of type cis-[Pd(FH)2Cl2]. The structure of palladium(II) complex was optimized and theoretical data show good agreement with the experimental results. The cytotoxic activity was evaluated in a chronic myelogenous leukemia cell line, which revealed that the compound is less active than cisplatin or carboplatin. At 300 g mL−1, the complex presented antimicrobial activity more efficient than ampicillin, chloranfenicol and kanamicyn.
URI: https://hrcak.srce.hr/105586
http://repositorio.ufla.br/jspui/handle/1/40770
Appears in Collections:DQI - Artigos publicados em periódicos

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