Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/41660
Título : Can post-exposure prophylaxis for COVID-19 be considered as an outbreak response strategy in long-term care hospitals?
Autor: Lee, Sun Hee
Son, Hyunjin
Peck, Kyong Ra
Palavras-chave: Post-exposure prophylaxis
Hydroxychloroquine
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
COVID-19
Long-term care hospital
Publicador: Elsevier
Data da publicação: Jun-2020
Referência: LEE, S. H.; SON, H.; PECK, K. R. Can post-exposure prophylaxis for COVID-19 be considered as an outbreak response strategy in long-term care hospitals? International Journal of Antimicrobial Agents, [S.l.], v. 55, n. 6, June 2020.
Abstract: In the context of the ongoing global outbreak of coronavirus disease 2019 (COVID-19), management of exposure events is a concern. Long-term care hospitals (LTCHs) are particularly vulnerable to cluster outbreaks because facilities for patient isolation and healthcare personnel to care for these patients in isolation are difficult to arrange in a large outbreak situation. Although several drugs have been proposed as treatment options, there are no data on the effectiveness and safety of post-exposure prophylaxis (PEP) for COVID-19. After a large COVID-19 exposure event in an LTCH in Korea, PEP using hydroxychloroquine (HCQ) was administered to 211 individuals, including 189 patients and 22 careworkers, whose baseline polymerase chain reaction (PCR) tests for COVID-19 were negative. PEP was completed in 184 (97.4%) patients and 21 (95.5%) careworkers without serious adverse events. At the end of 14 days of quarantine, all follow-up PCR tests were negative. Based on our experience, further clinical studies are recommended for COVID-19 PEP.
URI: https://www.sciencedirect.com/science/article/pii/S092485792030145X
http://repositorio.ufla.br/jspui/handle/1/41660
Idioma: en_US
Aparece nas coleções:FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19)

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