Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/11659
Title: Nuclear anomalies in the buccal cells of children under dental treatment
Keywords: Genotoxicity
Micronucleus tests
Dental materials
Genotoxicidade
Issue Date: 2011
Publisher: Universidade da Região de Joinville- Univille
Citation: REZENDE, E. de F. et al. Nuclear anomalies in the buccal cells of children under dental treatment. Revista Sul Brasileira de Odontologia, Joinville, v. 8, n. 2,p. 182-188, Apr./Jun. 2011.
Abstract: Introduction: Since some dental materials may be aggressive to a person’s body, studies involving such materials seem to be necessary. Objective: This study was conducted to evaluate the genotoxicity of dental materials through micronucleus (MN) test. Material and methods: Exfoliated buccal cells of 4-to-12 year-old children, who were on some type of dental treatment, were collected either before or after the treatment ending. Each sample was composed of 1,000 cells per patient. Student’s t test was used for comparison. Results: The dental materials were divided into 3 groups, as follows: cement, monomers, and their combination. Treatments using monomer + cement-based materials were found to increase significantly the number of binucleated (BN) cells, (p < 0.05) which indicate several degenerative nuclear changes. Conclusion: The combination of cement-based dental material with monomers increases the cytotoxic action of dental materials.
URI: http://vdisk.univille.edu.br/community/depto_odontologia/get/ODONTOLOGIA/RSBO/RSBO_v8_n2_abril-junho2011/v8n2a08.pdf
http://repositorio.ufla.br/jspui/handle/1/11659
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