Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/32511
Registro completo de metadados
Campo DCValorIdioma
dc.creatorLourenção, Bruna C.-
dc.creatorMedeiros, Roberta A.-
dc.creatorThomasi, Sérgio Scherrer-
dc.creatorFerreira, Antonio Gilberto-
dc.creatorRocha-Filho, Romeu C.-
dc.creatorFatibello-Filho, Orlando-
dc.date.accessioned2019-01-25T09:21:33Z-
dc.date.available2019-01-25T09:21:33Z-
dc.date.issued2016-01-
dc.identifier.citationLOURENCAO, B. C. et al. Amperometric flow-injection determination of the anthelmintic drugs ivermectin and levamisole using electrochemically pretreated boron-doped diamond electrodes. Sensors and Actuators B: Chemical, Lausanne, v. 222, p. 181-189, Jan. 2016.pt_BR
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0925400515302148#!pt_BR
dc.identifier.urihttp://repositorio.ufla.br/jspui/handle/1/32511-
dc.description.abstractSensitive, simple, low-cost, and rapid amperometric flow-injection methods were developed for determination of ivermectin (IVM) and levamisole (LVM) in anthelmintic pharmaceutical drugs and urine samples. These determinations were carried out with a cathodically (for IVM) or anodically (for LVM) pretreated boron-doped diamond electrode using aqueous 0.5 mol L−1 H2SO4 (with and without addition of 30% V/V of ethanol) as supporting electrolyte. The amperometric detection was performed at an applied electrode potential of E = 1.40 V, for IVM, and E = 1.90 V, for LVM, vs. Ag/AgCl (3.0 mol L−1 KCl). The respective analytical curves presented good linearity in the investigated concentration ranges (0.60–50 μmol L−1, for IVM, and 0.010–5.0 μmol L−1, for LVM) and the detection limits were 0.30 μmol L−1 for IVM, and 1 nmol L−1, for LVM. Investigation of possible interferents showed no significant interference with the here-proposed methods; thus, they were used to determine IVM and LVM in pharmaceutical formulations as well as in urine samples, with results that showed good agreement with comparative methods. Furthermore, a mechanism for LVM electrooxidation was proposed using exhaustive potentiostatic electrolysis and NMR measurements.pt_BR
dc.languageen_USpt_BR
dc.publisherElsevierpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceSensors and Actuators B: Chemicalpt_BR
dc.subjectIvermectinpt_BR
dc.subjectLevamisolept_BR
dc.subjectAmperometric detectionpt_BR
dc.subjectElectrochemical pretreatmentpt_BR
dc.subjectIvermectinapt_BR
dc.subjectDetecção amperométricapt_BR
dc.subjectPré-tratamento eletroquímicopt_BR
dc.titleAmperometric flow-injection determination of the anthelmintic drugs ivermectin and levamisole using electrochemically pretreated boron-doped diamond electrodespt_BR
dc.typeArtigopt_BR
Aparece nas coleções:DQI - Artigos publicados em periódicos

Arquivos associados a este item:
Não existem arquivos associados a este item.


Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.