Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/45375
Título : Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: a systematic review and meta-analysis
Autor: Liu, Ming
Gao, Ya
Yuan, Yuan
Yang, Kelu
Shi, Shuzhen
Tian, Jinhui
Zhang, Junhua
Palavras-chave: COVID-19
Lianhuaqingwen
Herbal medicine
Systematic review
Meta-analysis
Publicador: Elsevier
Data da publicação: Mar-2021
Referência: LIU, M. et al. Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: a systematic review and meta-analysis. Integrative Medicine Research, [S.l.], v. 10, n. 1, Mar. 2021.
Abstract: Background Lianhuaqingwen (LH) has been proven effective for influenza. However, the promotion of LH for the treatment of patients with COVID-19 remains controversial. Therefore, our study aimed to assess the efficacy and safety of Lianhuaqingwen (LH) in treating patients with COVID-19 by a systematic review and meta-analysis. Methods We conducted the literature search using six electronic databases from December 1, 2019, to June 2, 2020. Cochrane Risk of Bias tool was used to assess the quality of randomized controlled trials. Newcastle-Ottawa Scale was used to assess the quality of case control studies. Agency for Healthcare Research and Quality checklist was used to assess the quality of case series. All analyses were conducted by RevMan 5.3. For outcomes that could not be meta-analyzed were performed a descriptive analysis. Results Eight studies with 924 patients were included. Three studies were RCTs, three were case control studies, and two were case series. The quality of the included studies was poor. Compared with patients treated by conventional treatment, patients treated by LH combined with conventional treatment have a higher overall effective rate (RR = 1.16, 95%CIs: 1.04∼1.30, P = 0.01) and CT recovery rate (RR=1.21, 95%CIs: 1.02∼1.43, P = 0.03). Patients of LH groups have a lower incidence of diarrhea (5.6% vs.13.4%), and have statistically significant (P = 0.026). But the rate of abnormal liver function in the combined medication group is higher than that in the single LH group. Conclusion LH combined with conventional treatment seems to be more effective for patients with mild or ordinary COVID-19.
URI: https://www.sciencedirect.com/science/article/pii/S2213422020302766
http://repositorio.ufla.br/jspui/handle/1/45375
Idioma: en_US
Aparece nas coleções:FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19)

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