Use este identificador para citar ou linkar para este item: http://repositorio.ufla.br/jspui/handle/1/56490
Título: Twisting development, the birth of a potential new gene
Palavras-chave: Molecular biology
Evolutionary biology
Plant development
Biologia molecular
Biologia evolutiva
Desenvolvimento vegetal
Data do documento: Dez-2022
Editor: Elsevier
Citação: MARSCH-MARTÍNEZ, N. et al. Twisting development, the birth of a potential new gene. iScience, Cambridge, v. 25, n. 12, 105627, Dec. 2022. DOI: https://doi.org/10.1016/j.isci.2022.105627.
Resumo: Evolution has long been considered to be a conservative process in which new genes arise from pre-existing genes through gene duplication, domain shuffling, horizontal transfer, overprinting, retrotransposition, etc. However, this view is changing as new genes originating from non-genic sequences are discovered in different organisms. Still, rather limited functional information is available. Here, we have identified TWISTED1 (TWT1), a possible de novo-originated protein-coding gene that modifies microtubule arrangement and causes helicoidal growth in Arabidopsis thaliana when its expression is increased. Interestingly, even though TWT1 is a likely recent gene, the lack of TWT1 function affects A. thaliana development. TWT1 seems to have originated from a non-genic sequence. If so, it would be one of the few examples to date of how during evolution de novo genes are integrated into developmental cellular and organismal processes.
URI: http://repositorio.ufla.br/jspui/handle/1/56490
Aparece nas coleções:DBI - Artigos publicados em periódicos

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
ARTIGO_Twisting development, the birth of a potential new gene.pdf3,78 MBAdobe PDFVisualizar/Abrir


Este item está licenciada sob uma Licença Creative Commons Creative Commons