Please use this identifier to cite or link to this item: http://repositorio.ufla.br/jspui/handle/1/57836
Title: Ressonância magnética na avaliação de enxerto osteocondral autógeno na cartilagem articular de coelhos
Other Titles: Magnetic resonance in the evaluation of autogenous osteochondral graft in articular cartilage of rabbits
Keywords: Imagem por ressonância magnética
Enxerto osteocondral autógeno
Cartilagem articular
Coelhos
Magnetic resonance imaging
Autogenous osteochondral graft
Articular cartilage
Rabbits
Issue Date: 2017
Publisher: Colégio Brasileiro de Patologia Animal - CBPA. Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
Citation: KAWAMOTO, F. Y. K. et al. Ressonância magnética na avaliação de enxerto osteocondral autógeno na cartilagem articular de coelhos. Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 5, p. 502-510, 2017.
Abstract: This study aimed to determine the characteristics and applicability of magnetic resonance imaging (MRI) in the evaluation of autogenous osteochondral graft in intact or macerated format, with or without insulin-like growth factor type 1 (IGF-1) used in repair of cartilage lesions induced in rabbits. Nine New Zealand rabbits were used, in which 18 stifle joints underwent grafting procedure in the femoral trochlear groove. These were divided into four groups, referred as intact osteochondral graft + IGF-1 (n=5), intact osteochondral graft + saline solution (n=4), macerated osteochondral graft + IGF-1 (n=5) and macerated osteochondral graft + saline solution (n=4). Animals were euthanized 12 weeks after surgery and the joints were subjected to MRI using a high magnetic field scanner of 1.5 Tesla. In addition, samples of grafting sites were subjected to anatomopathological examination. The MRI was effective as a noninvasive method to evaluate the repair tissue in osteochondral grafts in articular cartilage of the femur of rabbits by providing complementary data to macroscopic and histological examinations. Through these images and anatomopathological examinations satisfactory results were observed in relation to the repair process of autogenous osteochondral grafts in cartilage of rabbits, regardless of its format or the addition of IGF-1.
URI: http://repositorio.ufla.br/jspui/handle/1/57836
Appears in Collections:DMV - Artigos publicados em periódicos

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