Anxiety-associated behavior and genotoxicity found in adult Danio rerio exposed to tebuconazole-based commercial product

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dc.creatorCastro, Tássia Flávia Dias
dc.creatorSouza, José Gilmarda Silva
dc.creatorCarvalho, Aline Ferreira Souza de
dc.creatorAssis, Isadora de Lima
dc.creatorPalmieri, Marcel José
dc.creatorVieira, Larissa Fonseca Andrade
dc.creatorMarcussi, Silvana
dc.creatorMachado, Monica Rodrigues Ferreira
dc.creatorMurgas, Luis David Solis
dc.date.accessioned2019-03-23T15:05:00Z
dc.date.available2019-03-23T15:05:00Z
dc.date.issued2018-09
dc.description.abstractThe effects of different concentrations of commercial product based on tebuconazole, on adults of Danio rerio, were evaluated through novel tank diving test and micronucleus and comet assay tests. A total of 320 adult D. rerio were divided into eight tanks and exposed to concentrations of 0; 100; 200 and 300 μg/L the commercial product based on tebuconazole, with their respective replicates at 24, 72 and 96 h. The results showed a behavioral deviation of zebrafish and a significant (p < 0.05) increase in DNA damage as a function of exposed time and different concentrations of the commercial product in relation to the negative control. The results obtained in this study allow to conclude that tebuconazole has effects on adults of Danio rerio, inducing genotoxicity and mutagenicity, as well as altering neurological functions related to the change in the behavior of adults.pt_BR
dc.identifier.citationCASTRO, T. F. D. et al. Anxiety-associated behavior and genotoxicity found in adult Danio rerio exposed to tebuconazole-based commercial product. Environmental Toxicology and Pharmacology, [S.l.], v. 62, p. 140-146, Sept. 2018. DOI: 10.1016/j.etap.2018.06.011.pt_BR
dc.identifier.urihttps://repositorio.ufla.br/handle/1/33277
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1382668918301546pt_BR
dc.languageen_USpt_BR
dc.publisherElsevierpt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceEnvironmental Toxicology and Pharmacologypt_BR
dc.subjectTriazolept_BR
dc.subjectComet assaypt_BR
dc.subjectMicronucleus testpt_BR
dc.titleAnxiety-associated behavior and genotoxicity found in adult Danio rerio exposed to tebuconazole-based commercial productpt_BR
dc.typeArtigopt_BR

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