Approaches and challenges in SARS-CoV-2 vaccine development

dc.creator	Dagotto, Gabriel
dc.creator	Yu, Jingyou
dc.creator	Barouch, Dan H.
dc.date.accessioned	2020-09-22T17:45:05Z
dc.date.available	2020-09-22T17:45:05Z
dc.date.issued	2020-09
dc.description.abstract	The explosive spread of SARS-CoV-2 suggests that a vaccine will be required to end this global pandemic. Progress in SARS-CoV-2 vaccine development to date has been faster than for any other pathogen in history. Multiple SARS-CoV-2 vaccine candidates have been evaluated in preclinical models and are currently in clinical trials. In this Perspective, we discuss three topics that are critical for SARS-CoV-2 vaccine development: antigen selection and engineering, preclinical challenge studies in non-human primate models, and immune correlates of protection.	pt_BR
dc.identifier.citation	DAGOTTO, G.; YU, J.; BAROUCH, D. H. Approaches and challenges in SARS-CoV-2 vaccine development. Cell Host & Microbe, [S.l.], v. 28, n. 3, p. 364-370, Sept. 2020.	pt_BR
dc.identifier.uri	https://repositorio.ufla.br/handle/1/43154
dc.identifier.uri	https://www.sciencedirect.com/science/article/pii/S1931312820304558	pt_BR
dc.language	en_US	pt_BR
dc.publisher	Cell Press	pt_BR
dc.rights	openAccess	pt_BR
dc.source	Cell Host & Microbe	pt_BR
dc.subject	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)	pt_BR
dc.subject	COVID-19 - Vaccine	pt_BR
dc.title	Approaches and challenges in SARS-CoV-2 vaccine development	pt_BR
dc.type	Artigo	pt_BR

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