Is COVID-19 receiving ADE from other coronaviruses?

dc.creator	Tetro, Jason A.
dc.date.accessioned	2020-03-26T17:21:49Z
dc.date.available	2020-03-26T17:21:49Z
dc.date.issued	2020-03
dc.description.abstract	One of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deaths. ADE also requires prior exposure to similar antigenic epitopes, presumably circulating in local viruses, making it a possible explanation for the observed geographic limitation of severe cases and deaths.	pt_BR
dc.identifier.citation	TETRO, J. A. Is COVID-19 receiving ADE from other coronaviruses? Microbes and Infection, v. 22, n. 2, p. 72-73, Mar. 2020.	pt_BR
dc.identifier.uri	https://repositorio.ufla.br/handle/1/39433
dc.identifier.uri	https://www.sciencedirect.com/science/article/pii/S1286457920300344	pt_BR
dc.language	en_US	pt_BR
dc.publisher	Elsevier	pt_BR
dc.rights	openAccess	pt_BR
dc.source	Microbes and Infection	pt_BR
dc.subject	COVID-19	pt_BR
dc.subject	Coronavirus	pt_BR
dc.subject	Antibody dependent enhancement (ADE)	pt_BR
dc.title	Is COVID-19 receiving ADE from other coronaviruses?	pt_BR
dc.type	Artigo	pt_BR

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