Citocalasinas produzidas por Xylaria sp., um fungo endofítico de Piper aduncum (piperaceae)

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dc.contributor.authorSilva, Geraldo H.
dc.contributor.authorOliveira, Camila M. de
dc.contributor.authorTeles, Helder L.
dc.contributor.authorBolzani, Vanderlan da Silva
dc.contributor.authorAraújo, Angela Regina
dc.contributor.authorPfenning, Ludwig H.
dc.contributor.authorYoung, Maria Claudia M.
dc.contributor.authorCosta-Neto, Claudio M.
dc.contributor.authorHaddad, Renato
dc.contributor.authorEberlin, Marcos N.
dc.date.accessioned2020-02-18T20:11:42Z
dc.date.available2020-02-18T20:11:42Z
dc.date.issued2010
dc.description.abstractA chemical study on the EtOAc extract produced by Xylaria sp., an endophytic fungus from Piper aduncum, resulted in the isolation of a new cytochalasin 1, along with five known 19,20-epoxycytochalasin D (2), C (3), N (4), Q (5), and R (6). The 1-6 were evaluated against the fungi C. cladosporioides and C. sphaerospermum and only 5 showed weak activity. The cytotoxicity in vitro against HeLA and CHO cells lines were investigated and the cytochalasins 2-4, and 6 showed a strong activity against HeLA. The DNAdamaging activity of 1-6 were also investigated against mutant strains of S. cerevisiae.pt_BR
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dc.description.provenanceApproved for entry into archive by Eliana Bernardes (eliana@biblioteca.ufla.br) on 2020-02-18T20:11:42Z (GMT) No. of bitstreams: 2 ARTIGO_Citocalasinas produzidas por Xylaria sp., um fungo endofítico de Piper aduncum (piperaceae).pdf: 198980 bytes, checksum: ccb17061fce944dc07fdce80ef8dd58c (MD5) license_rdf: 913 bytes, checksum: 3ed9dcfcdaa138fb3ca7d7db99308a28 (MD5)en
dc.description.provenanceMade available in DSpace on 2020-02-18T20:11:42Z (GMT). No. of bitstreams: 2 ARTIGO_Citocalasinas produzidas por Xylaria sp., um fungo endofítico de Piper aduncum (piperaceae).pdf: 198980 bytes, checksum: ccb17061fce944dc07fdce80ef8dd58c (MD5) license_rdf: 913 bytes, checksum: 3ed9dcfcdaa138fb3ca7d7db99308a28 (MD5) Previous issue date: 2010en
dc.identifier.citationSILVA, G. H. et al. Citocalasinas produzidas por Xylaria sp., um fungo endofítico de Piper aduncum (piperaceae). Química Nova, São Paulo, v. 33, n. 10, p. 2038-2041, 2010.pt_BR
dc.identifier.urihttps://repositorio.ufla.br/handle/1/39045
dc.languagept_BRpt_BR
dc.publisherSociedade Brasileira de Químicapt_BR
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsAttribution-NonCommercial 4.0 International
dc.rightsrestrictAccesspt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.sourceQuímica Novapt_BR
dc.subjectXylaria sp.pt_BR
dc.subjectPiper aduncumpt_BR
dc.subjectEndophytic funguspt_BR
dc.titleCitocalasinas produzidas por Xylaria sp., um fungo endofítico de Piper aduncum (piperaceae)pt_BR
dc.title.alternativeCytochalasins produced by Xylaria sp., an endophytic fungus from Piper aduncumpt_BR
dc.typeArtigopt_BR

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