A new complex of Palladium(II) with 2-furoic hydrazide: synthesis, characterization, theoretical calculations and biological studies

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dc.creatorSouza, Gustavo Duarte de
dc.creatorRodrigues, Mônica Aparecida
dc.creatorSilva, Priscila Pereira
dc.creatorPereira-Maia, Elene Cristina
dc.creatorBotelho, Françoise Vasconcelos
dc.creatorCampos, Tatiana Amabile de
dc.creatorFranca, Eduardo de Faria
dc.creatorAlmeida, Katia Júlia de
dc.creatorGuerra, Wendell
dc.date.accessioned2020-05-10T20:55:14Z
dc.date.available2020-05-10T20:55:14Z
dc.date.issued2013
dc.description.abstractA new complex of palladium was isolated with 2-furoic hydrazide (FH) and characterized by spectroscopic methods. The results show that the ligand is coordinated to palladium by the basic nitrogen of NH2 group and has a general structure of type cis-[Pd(FH)2Cl2]. The structure of palladium(II) complex was optimized and theoretical data show good agreement with the experimental results. The cytotoxic activity was evaluated in a chronic myelogenous leukemia cell line, which revealed that the compound is less active than cisplatin or carboplatin. At 300 g mL−1, the complex presented antimicrobial activity more efficient than ampicillin, chloranfenicol and kanamicyn.pt_BR
dc.identifier.citationSOUZA, G. D. de et al. A new complex of Palladium(II) with 2-furoic hydrazide: synthesis, characterization, theoretical calculations and biological studies. Croatica Chemica Acta, [S.l.], v. 86, n. 2, p. 201-206, 2013. DOI: 10.5562/cca2151.pt_BR
dc.identifier.urihttps://repositorio.ufla.br/handle/1/40770
dc.identifier.urihttps://hrcak.srce.hr/105586pt_BR
dc.languageen_USpt_BR
dc.publisherCroatian Chemical Societypt_BR
dc.rightsrestrictAccesspt_BR
dc.sourceCroatica Chemica Actapt_BR
dc.subjectPalladium complexespt_BR
dc.subjectHydrazidespt_BR
dc.subjectHydrazonespt_BR
dc.subjectDFTpt_BR
dc.subjectDensity functional theorypt_BR
dc.subjectAntibacterial activitypt_BR
dc.titleA new complex of Palladium(II) with 2-furoic hydrazide: synthesis, characterization, theoretical calculations and biological studiespt_BR
dc.typeArtigopt_BR

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