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http://repositorio.ufla.br/jspui/handle/1/43407| Título : | Point of view: should COVID-19 patients be supplemented with vitamin D? |
| Autor: | Annweiler, Cédric Cao, Zhijian Sabatier, Jean-Marc |
| Palavras-chave: | COVID-19 - Treatment Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vitamin D |
| Publicador: | Elsevier |
| Data da publicação: | Out-2020 |
| Referência: | ANNWEILER, C.; CAO, Z.; SABATIER, J.-M. Point of view: should COVID-19 patients be supplemented with vitamin D? Maturitas, [S.l.], v. 140, p. 24-26, Oct. 2020. |
| Abstract: | Using Hill's methodology for exploring causality, we aimed to determine in early May 2020 whether evidence supports vitamin D as a biological determinant of COVID-19 outcomes. Vitamin D is a secosteroid hormone theoretically able to reduce COVID-19 risk through regulation of (i) the renin-angiotensin system, (ii) cellular innate and adaptive immunity, and (iii) physical barriers. Inverse associations were found between 25-hydroxyvitamin D concentrations and COVID-19 incidence and mortality. Randomized controlled trials testing vitamin D supplementation in the treatment of COVID-19 are in progress. Positive results in such studies would encourage the use of vitamin D supplements as an adjuvant treatment in COVID-19. |
| URI: | https://www.sciencedirect.com/science/article/pii/S0378512220302929 http://repositorio.ufla.br/jspui/handle/1/43407 |
| Idioma: | en_US |
| Aparece nas coleções: | FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19) |
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