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http://repositorio.ufla.br/jspui/handle/1/43407| metadata.artigo.dc.title: | Point of view: should COVID-19 patients be supplemented with vitamin D? |
| metadata.artigo.dc.creator: | Annweiler, Cédric Cao, Zhijian Sabatier, Jean-Marc |
| metadata.artigo.dc.subject: | COVID-19 - Treatment Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vitamin D |
| metadata.artigo.dc.publisher: | Elsevier |
| metadata.artigo.dc.date.issued: | Oct-2020 |
| metadata.artigo.dc.identifier.citation: | ANNWEILER, C.; CAO, Z.; SABATIER, J.-M. Point of view: should COVID-19 patients be supplemented with vitamin D? Maturitas, [S.l.], v. 140, p. 24-26, Oct. 2020. |
| metadata.artigo.dc.description.abstract: | Using Hill's methodology for exploring causality, we aimed to determine in early May 2020 whether evidence supports vitamin D as a biological determinant of COVID-19 outcomes. Vitamin D is a secosteroid hormone theoretically able to reduce COVID-19 risk through regulation of (i) the renin-angiotensin system, (ii) cellular innate and adaptive immunity, and (iii) physical barriers. Inverse associations were found between 25-hydroxyvitamin D concentrations and COVID-19 incidence and mortality. Randomized controlled trials testing vitamin D supplementation in the treatment of COVID-19 are in progress. Positive results in such studies would encourage the use of vitamin D supplements as an adjuvant treatment in COVID-19. |
| metadata.artigo.dc.identifier.uri: | https://www.sciencedirect.com/science/article/pii/S0378512220302929 http://repositorio.ufla.br/jspui/handle/1/43407 |
| metadata.artigo.dc.language: | en_US |
| Appears in Collections: | FCS - Artigos sobre Coronavirus Disease 2019 (COVID-19) |
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