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http://repositorio.ufla.br/jspui/handle/1/58184| Title: | Development of an electrochemical sensor modified with dealuminated zeolite with citric acid for hydroxyzine determination by BIA-Amperometry |
| Keywords: | Batch Injection analysis Amperometric sensor Carbon paste electrodes Hydroxyzine Zeolite |
| Issue Date: | 2023 |
| Publisher: | Visão Fokka Communication Agency |
| Citation: | FELIX, F. da S. et al. Development of an electrochemical sensor modified with dealuminated zeolite with citric acid for hydroxyzine determination by BIA-Amperometry. Brazilian Journal of Analytical Chemistry, [S.l.], v. 10, n. 40, p. 65-75, 2023. |
| Abstract: | An electrochemical sensor modified with zeolite dealuminated with citric acid was developed for the determination of hydroxyzine in pharmaceutical products during BIA-amperometry experiments. The modified electrochemical sensor was prepared by mixing powdered graphite with zeolite treated with citric acid homogenized with hexane and mineral oil (60:20:20% w/w/w respectively). The developed sensor showed reproducible amperometric responses in a linear range of 1.0x10-6 – 2.0x10-5 mol L-1 in +1,28 V (vs. Ag/AgCl). The detection limit and detection limit found were 3.10x10-7 mol L-1 e 1.04x10-6 mol L-1, respectively. The method developed by BIA-amperometry was applied for the determination of the analyte in tablets and commercial syrups and the results found agreement with the nominal values of the commercial samples. |
| URI: | https://brjac.com.br/artigos/brjac-93-2022.pdf http://repositorio.ufla.br/jspui/handle/1/58184 |
| Appears in Collections: | DQI - Artigos publicados em periódicos |
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