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Dihydroisocoumarins produced by Xylaria sp. and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophylla
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The dihydroisocoumarin (3R,4R)-3,4-dihydro-4,6-dihydroxy-3-methyl-1-oxo-1H-isochromene-5-carboxylic acid (1) was isolated from Xylaria sp., a fungus associated with Piper aduncum (Piperaceae). Additionally, two known compounds, (R)-7-hydroxymellein (2) and (3R,4R)-4,7-dihydroxymellein (3), were isolated from Penicillium sp. associated to Alibertia macrophylla (Rubiaceae). The structures of all compounds were elucidated by analysis of spectroscopic data. The dihydrocoumarin derivatives 1–3 showed antifungal and acetylcholinesterase (AChE) inhibitory activities in vitro.
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Submitted by Eliana Bernardes (eliana@biblioteca.ufla.br) on 2020-02-19T12:39:37Z
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Approved for entry into archive by Eliana Bernardes (eliana@biblioteca.ufla.br) on 2020-02-19T12:39:56Z (GMT) No. of bitstreams: 0
Made available in DSpace on 2020-02-19T12:39:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-06
Approved for entry into archive by Eliana Bernardes (eliana@biblioteca.ufla.br) on 2020-02-19T12:39:56Z (GMT) No. of bitstreams: 0
Made available in DSpace on 2020-02-19T12:39:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-06
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OLIVEIRA, C. M. et al. Dihydroisocoumarins produced by Xylaria sp. and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophylla. Phytochemistry Letters, [S.l.], v. 4, n. 2, p. 93-96, June 2011.
