1,4-Dihydropyridine derivatives: an overview of synthesis conditions and biological tests

Carregando...
Imagem de Miniatura

Notas

Orientadores

Coorientadores

Membros de banca

Título da Revista

ISSN da Revista

Título de Volume

Editor

Bentham Science

Faculdade, Instituto ou Escola

Departamento

Programa de Pós-Graduação

Agência de fomento

Tipo de impacto

Áreas Temáticas da Extenção

Objetivos do desesenvolvimento sustentável

Dados abertos

Resumo

Abstract

1,4-dihydropyridine is a versatile class of compounds with multiple biological activities, thus holding significant pharmacological potential. Recent studies have provided evidence concerning the anticancer, antimicrobial, and anti-inflammatory properties of 1,4-dihydropyridines, as well as their potential in Alzheimer's disease treatment. Therefore, this class of compounds is a promising candidate in studies of drug development and drug discovery. The major derivatives of 1,4-dihydropyridine can be synthesized through one-pot synthesis in many different ways, varying the solvents, catalysts, and experimental conditions. Due to the compound's remarkable potential and ease of production, in this review we aimed to present the biological activities and synthesis methodologies of the main 1,4-dihydropyridine derivatives reported by scientific literature over the past decade.

Descrição

Área de concentração

Agência de desenvolvimento

Palavra chave

Marca

Objetivo

Procedência

Impacto da pesquisa

Resumen

ISBN

DOI

Citação

LAGO, A. F. S.; BENEDICTO, D. F. C.; SILVA, L.; THOMASI, S. 1,4-Dihydropyridine derivatives: an overview of synthesis conditions and biological tests. Current Medicinal Chemistry, [S.l.], v. 27, out.2023. DOI: 10.2174/0113852728264228231013074432

Link externo

Avaliação

Revisão

Suplementado Por

Referenciado Por